Why are there folds in the brain




















This explanation puts other, more complex theories to rest. But as far as the most recent evidence goes, it appears that evolution favored a simpler explanation: The brain simply crumples up because it grows too quickly in a small space.

Schizophrenia may have a special fingerprint in the brain, even before its symptoms fully emerge. Now, a new method of analyzing this fingerprint — found within the folds of the brain — could help predict which young adults at high risk for schizophrenia will go on to develop the illness, a new study suggests. The method, which was based on MRI scans of the brain, looked at the correlation between the amount of folding in different brain areas, which can reflect the strength of underlying connections between those areas.

Using this method, the researchers could predict the outcome of 79 high-risk individuals with 80 percent accuracy, they reported yesterday April 25 in the journal JAMA Psychiatry.

These findings need to be confirmed in larger future studies before the method can be used to in the clinic, the researchers said. But the goal is to find what clues from the brain's structure could help clinicians better identify and treat patients before they experience full-blown schizophrenia and drop out of schools or lose their jobs due to a psychotic episode, said study investigator Dr.

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An arching tract of nerve cells leads from the hypothalamus and the thalamus to the hippocampus This tiny nub acts as a memory indexer—sending memories out to the appropriate part of the cerebral hemisphere for long-term storage and retrieving them when necessary. The basal ganglia not shown are clusters of nerve cells surrounding the thalamus.

They are responsible for initiating and integrating movements. The brain and the rest of the nervous system are composed of many different types of cells, but the primary functional unit is a cell called the neuron. All sensations, movements, thoughts, memories, and feelings are the result of signals that pass through neurons. Neurons consist of three parts. The cell body 13 contains the nucleus, where most of the molecules that the neuron needs to survive and function are manufactured.

Dendrites 14 extend out from the cell body like the branches of a tree and receive messages from other nerve cells. Signals then pass from the dendrites through the cell body and may travel away from the cell body down an axon 15 to another neuron, a muscle cell, or cells in some other organ. The neuron is usually surrounded by many support cells. Some types of cells wrap around the axon to form an insulating sheath This sheath can include a fatty molecule called myelin, which provides insulation for the axon and helps nerve signals travel faster and farther.

Or axons may be very long, such as those that carry messages from the brain all the way down the spinal cord. Scientists have learned a great deal about neurons by studying the synapse—the place where a signal passes from the neuron to another cell.

When the signal reaches the end of the axon it stimulates the release of tiny sacs These sacs release chemicals known as neurotransmitters 18 into the synapse The neurotransmitters cross the synapse and attach to receptors 20 on the neighboring cell. These receptors can change the properties of the receiving cell. If the receiving cell is also a neuron, the signal can continue the transmission to the next cell.

Neurotransmitters are chemicals that brain cells use to talk to each other. Some neurotransmitters make cells more active called excitatory while others block or dampen a cell's activity called inhibitory. Acetylcholine is an excitatory neurotransmitter because it generally makes cells more excitable.

It governs muscle contractions and causes glands to secrete hormones. Glutamate is a major excitatory neurotransmitter. Too much glutamate can kill or damage neurons and has been linked to disorders including Parkinson's disease, stroke, seizures, and increased sensitivity to pain.



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